Deep Vein Thrombosis
How is it treated?
Deep vein thrombosis (DVT) is usually treated with anticoagulants such as heparin and warfarin--medications that prevent the blood from clotting (coagulating) any further. This allows the body's natural defenses to break down existing clots gradually. Occasionally, drugs that actually dissolve clots are used. These "clot busters" are not commonly used for DVT, however, unless a serious risk of life-threatening complications exists.
Injectable and oral anticoagulants are used for treatment. The injectable medication is usually given along with the oral medication during the first week or until the oral medication becomes fully effective. The oral medication is then continued for prevention of a repeat DVT for 3 to 6 months for most patients. Sometimes it may be necessary to remain on the oral medication longer. This is dependent on your previous history of a DVT episode or continuous risk factors such as cancer or hereditary diseases.
When taking the oral anticoagulant, it is important to note that your doctor will require very careful monitoring of the medication, and it may be necessary to change your dose periodically. Your doctor or pharmacist will use a blood test that measures your International Normalized Ratio (INR) to adjust your dose. It is important to take the medication exactly as directed by your doctor or pharmacist to ensure that you are not at risk to develop another DVT or increased bleeding.
Drug classes used to treat Deep Vein Thrombosis Direct Thrombin Inhibitors Heparin Low Molecular Weight Heparins Oral Anticoagulants Selective Factor Xa Inhibitor (Pentasaccharide) Thrombolytic Agents
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