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Tricyclic Antidepressant & Benzodiazepine Combination
For patients with depression and anxiety, one product contains two types of drugs: a tricyclic antidepressant or TCA (amitriptyline) and a benzodiazepine (chlordiazepoxide or CDP). Tricyclic antidepressants (TCAs) work by increasing low amounts of certain chemicals (dopamine, norepinephrine, and serotonin) in the brain. Known as neurotransmitters, these chemicals help to regulate alertness, energy, mood, and motivation. Benzodiazepines are a group of drugs that affect another neurotransmitter, gamma-aminobutyric acid or GABA for short. Increased levels of GABA slow down the central nervous system to help relieve anxiety and produce an overall relaxing effect.
Usually, combination amitriptyline and chlordiazepoxide tablets are taken two times, three times, or four times a day. Generally, the largest part of the dose should be taken at bedtime because one of its main side effects is drowsiness. Other common side effects from amitriptyline and chlordiazepoxide include blurred vision, constipation, dizziness, loss of appetite, and restlessness. It also has many interactions with alcohol, non-prescription drugs, and prescription medications. Patients who take it for long periods may need to have blood tests and tests of liver function.
Drugs in the class
Amitriptyline; Chlordiazepoxide Tablets (Limbitrol, Limbitrol DS) |
