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Direct Thrombin Inhibitors

Direct thrombin inhibitors are used in the prevention and treatment of DVT. Direct thrombin inhibitors take the straightest path to prevent clots by interfering with the protein called "thrombin," which is considered the blood's chief clotting molecule.Thrombin shares its name with "thrombosis," the medical term for clotting. These medications unlike the other medications available inhibit both circulating and clot bound thrombin.

Drugs in the class

Argatroban ()

Lepirudin (Refludan)

Bivalirudin (Angiomax)


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.



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