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Treatment Options

Proton Pump Inhibitors

Hydrochloric acid is released by the proton pump (ATPase pump) located within the parietal cells of the stomach. Proton pump inhibitors bind to the ATPase enzyme, suppressing gastric acid output. They relieve pain and heal peptic ulcers faster than H2 blockers but are typically more expensive. Unlike the antacids the PPIs don?t offer immediate relief. When a patient uses PPIs the amount of acid released into his stomach is decreased for 3 to 4 days as more proton pumps are inhibited. When the PPI is stopped, the stomach starts producing more acid and is back to normal in 3 to 5 days.

Drugs in the class

Lansoprazole Delayed-Release Capsules (Lansoprazole Delayed-Release Capsule, Prevacid Delayed-Release Capsule)

Omeprazole capsules (Prilosec)

Esomeprazole Gastro-Resistant Capsules (Nexium Delayed-Release Capsules)

Pantoprazole (Protonix)

Rabeprazole (Aciphex)

Omeprazole OTC (Prilosec OTC)

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.