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Treatment Options

Non-steroidal Anti-inflammatory Drugs

Non-steroidal anti-inflammatory drugs (NSAIDs) work by suppressing the body?s production of fatty acids called prostaglandins, which contribute to the inflammation and pain of arthritis. Generally, NSAIDs block the action of an enzyme, cyclooxygenase (COX) that is responsible for making prostaglandins.

Many NSAIDs are now available without a prescription (over-the-counter or OTC) or as generic products. Although non-prescription NSAIDs are good options to relieve minor pain, many individuals with chronic inflammatory conditions such as rheumatoid arthritis (RA) may need stronger prescription-strength NSAIDs. All NSAIDs can have side effects, including confusion, diarrhea, headache, and swelling. Potentially dangerous side effects, such as bleeding in the stomach and worsened high blood pressure, can occur without warning signs. Thus, regular NSAID use should be monitored by a physician. Medications that protect the stomach can be prescribed with NSAIDs.

Drugs in the class

Piroxicam (Feldene)

Indomethacin Suppositories (Indocin Suppositories)

Diclofenac (Voltaren)

Tolmetin (TolectinTolectin DS)

Diclofenac Potassium (Cataflam)

Etodolac (Lodine)

Flurbiprofen Oral (Ansaid)

Ketoprofen (OrudisOruvail)

Meloxicam (Mobic)

Fenoprofen (Nalfon)

Nabumetone (Relafen)

Naproxen (AleveAnaproxAnaprox DSEC-NaprosynNaprelanNaprosyn)

Etodolac ER (Lodine XL)

Indomethacin SR (Indocin SR)

Oxaprozin (Daypro)

Diclofenac XR (Voltaren XR)

Sulindac (Clinoril)

Ibuprofen (AdvilAdvil Liqui-GelsAdvil MigraineGenprilHaltranJunior Strength AdvilJunior Strength MotrinMenadolMidol Maximum Strength Cramp FormulaMotrinMotrin IBMotrin Migrain PainNuprinRufen)

Indomethacin (Indocin)

Meclofenamate (Meclomen)


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.



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