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Treatment Options

Ergot Derivatives

Ergot Derivatives are an option for headaches that do not respond to aspirin, acetaminophen, NSAIDs, or triptans. Ergot derivatives are made in several different dosage forms such as quickly dissolving tablets, injections, and a nasal spray. Ergot derivatives have more serious side effects and require close monitoring by a healthcare provider. Patients should be aware that this drug may be habit forming. Side effects include abdominal cramping, nausea, dizziness, and dry mouth. Patients should report muscle pains, numbness, coldness, or loss of color in their hands or feet to their doctor immediately.

Drugs in the class

Caffeine, Ergotamine Tablets (Cafeine, Ergotamine TabletsCafergot Tablets)

Dihydroergotamine Injection (DHE 45 Injection)

Dihydroergotamine Nasal Spray (Migranal)


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.



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