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Histamine-2 Receptor Blockers

Within the parietal cells of the stomach is the ATPase pump, also called the proton pump, which releases hydrochloric acid. This pump is activated when histamine stimulates H2 receptors. H2 blockers prevent histamine from binding to H2 receptors and activating the ATPase pump, thereby reducing the amount of acid that is released. Drugs in this class are available in lower non-prescription doses and higher precription doses.

Drugs in the class

Ranitidine Tablets (Zantac 75Zantac Tablets)

Famotidine Chewable Tablets (Pepcid AC Chewable Tablets)

Ranitidine Oral Syrup (Zantac Syrup)

Nizatidine capsules (Axid ARAxid CapsulesNizatadine Capsules)

Cimetidine Tablets (TagametTagamet HB)

Ranitidine Hydrochloride Injection (Zantac Injection)

Ranitidine Effervescent Tablets or Granules (Zantac EFFERdose)

Famotidine Oral Suspension (Pepcid Oral Suspension)


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.



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