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Biguanides

The exact mechanism of the biguanides is not known, but the effects are well documented. Biguanides reduce insulin resistance in muscle cells and decrease the release of glucose from the liver. They also reduce the absorption of glucose in the small intestine, and may enhance insulin sensitivity inside the cell, as well as stimulate the disposal of glucose.

Because biguanides do not stimulate insulin secretion, they do not cause as much hypoglycemia (low blood sugar) compared to other diabetes medications. Biguanides may cause weight loss, which can be beneficial in obese patients.

Drugs in the class

Metformin Extended-Release (FortametGlucophage XRGlumetza)

Metformin (Glucophage)


Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It is not intended to diagnose a health condition, but it can be used as a guide to help you decide if you should seek professional treatment or to help you learn more about your condition once it has been diagnosed.



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