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ACE-Inhibitors
The kidneys produce the enzyme renin, which releases the hormone angiotensin I. Angiotensin converting enzyme (ACE) converts angiotensin I to angiotensin II, which constricts blood vessels and causes the kidneys to retain more fluid. The main function of angiotensin II is to increase the blood pressure. ACE inhibitors block the conversion of angiotensin I to angiotensin II, thereby reducing constriction and helping to reduce blood pressure.
A common side effect unique to drugs in this class is a persistent, dry cough. If you experience this side effect, alert your doctor. You may not experience this side effect with all medications in this class, so it may be beneficial to try a couple of different ACE-inhibitors before switching to a different class of antihypertensives. Drugs in the class
Benazepril
(
Lotensin
)
Captopril
(
Capoten
)
Enalapril Tablets
(
Enalapril Maleate Tablets,
Vasotec Tablets
)
Enalaprilat Solution for Injection
Fosinopril Tablets
(
Fosinopril Sodium Tablets,
Monopril Tablets
)
Lisinopril Tablets
(
Prinivil Tablets,
Zestril Tablets
)
Moexipril Tablets
(
Moexipril Hydrochloride Tablets,
Univasc Tablets
)
Perindopril Tablets
(
Aceon Tablets,
Perindopril Erbumine Tablets
)
Quinapril
(
Accupril
)
Ramipril Capsules
(
Altace Capsules
)
Trandolapril Tablets
(
Mavik
)
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