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Printable Version Tryptophan
Other Names: L-tryptophan

What side effects should I watch for?

Major Side Effects

In the early 1990s, the U.S. Food and Drug Administration (FDA) withdrew tryptophan from the U.S. market due to a rare but definite association with fatal or disabling eosinophilia-myalgia syndrome. Symptoms that include fatigue, fever, muscle and joint pain, rash, and swelling in the face, arms, or legs, may be caused by eosinophilia-myalgia syndrome. Some individuals may be more likely to experience problems, but who might be affected is impossible to determine before symptoms develop. The severity of the possible results is also unpredictable.

Less Severe Side Effects

Oral supplemental tryptophan has also been associated with less serious side effects that include:

  • Blurry vision
  • Drowsiness
  • Dry mouth
  • Headaches
  • Muscle incoordination
  • Nausea

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Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.

In general, herbal products are not subject to review or approval by the U.S. Food and Drug Administration (FDA). They are not required to be standardized, meaning that the amounts of active ingredients or contaminants they contain may vary between brands or between different batches of the same brand. Not all of the risks, side effects, or interactions associated with the use of herbal products are known because few reliable studies of their use in humans have been done.

This information is provided for your education only. Please share this information with your healthcare provider and be sure that you talk to your doctor and pharmacist about all the prescription and non-prescription medicines you take before you begin to use any herbal product.

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