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Herbs & Supplements

Creosote bush
Scientific Name: Chaparral
Other Names: Greaswood, Hediondilla, Larrea divaricata, Larrea glutinosa, Larrea tridentata, Stinkweed

References

American Cancer Society. Unproven Methods of Cancer Management. New York: American Cancer Society Press, 1982.

Anon: Chaparral. In: DerMarderosian A, Beutler JA, eds. Facts and Comparisons: The Review of Natural Products. St. Louis, MO, Facts and Comparisons. August 1993.

Batchelor WB, Heathcote J, Wanless IR. Chaparral-induced hepatic injury. American Journal of Gastroenterology. 1995;90(5):831-833.

Clark F, Reed DR. (1992) Chaparral-induced toxic hepatitis -- California and Texas, 1992. Morbidity and Mortality Weekly Report. 41(43):812-814.

Gordon DW, Rosenthal G, Hart J, Sirota R, Baker AL. Chaparral ingestion. The broadening spectrum of liver injury caused by herbal medications. Journal of the American Medical Association. 1995;273(6):489-490.

Heron S, Yarnell E. The safety of low-dose Larrea tridentata (DC) Coville (creosote bush or chaparral): a retrospective clinical study. Journal of Alternative and Complimentary Medicine. 2001;7(2):175-185.

Jellin JM, Gregory P, Batz F, Hitchens K, et al, eds. Pharmacist's Letter/Prescriber's Letter. Natural Medicines Comprehensive Database, 3rd Edition. Stockton CA: Therapeutic Research Facility, 2000.

Katz M, Saibil F. Herbal hepatitis: subacute hepatic necrosis secondary to chaparral leaf. Journal of Clinical Gastroenterology. 1990;12(2):203-206.

Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: Stonesong Press; 1999.

Shad JA, Chinn CG, Brann OS. Acute hepatitis after ingestion of herbs. Southern Medical Journal. 1999;92(11):1095-1097.

Sheikh NM, Philen RM, Love LA. Chaparral-associated hepatotoxicity. Archives of Internal Medicine. 1997;157(8):913-919.

Smith BC, Desmond PV. Acute hepatitis induced by ingestion of the herbal medication chaparral. Australia and New Zealand Medical Journal. 1993;23:526.

Last Revised April 27, 2006

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Note: The above information is not intended to replace the advice of your physician, pharmacist, or other healthcare professional. It is not meant to indicate that the use of the product is safe, appropriate, or effective for you.

In general, herbal products are not subject to review or approval by the U.S. Food and Drug Administration (FDA). They are not required to be standardized, meaning that the amounts of active ingredients or contaminants they contain may vary between brands or between different batches of the same brand. Not all of the risks, side effects, or interactions associated with the use of herbal products are known because few reliable studies of their use in humans have been done.

This information is provided for your education only. Please share this information with your healthcare provider and be sure that you talk to your doctor and pharmacist about all the prescription and non-prescription medicines you take before you begin to use any herbal product.

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